CDC25B Mouse Monoclonal Antibody [Clone ID: LBI6H9]
Product Specifications
Background
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) CDC25B mouse monoclonal antibody, clone LBI6H9
Synonyms
Cell division cycle 25 homolog B (S. pombe) ; cell division cycle 25B; OTTHUMP00000030137; OTTHUMP00000030138; OTTHUMP00000030139
Gene Name
Homo sapiens cell division cycle 25B (CDC25B), transcript variant 2, mRNA.
Gene ID
994
UniProt
P30305
Conjugation
Unconjugated
Related Pathways
Cell cycle, MAPK signaling pathway, Progesterone-mediated oocyte maturation
Field of Research
Cell cycle, MAPK signaling pathway, Progesterone-mediated oocyte maturation
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Phosphatase
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CDC25B
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=994
Uniprot URL
https://www.uniprot.org/uniprot/P30305
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