IL15RA Mouse Monoclonal Antibody [Clone ID: LBI6B2]
Product Specifications
Background
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Apr 2010]
Synonyms
CD215
Gene Name
Homo sapiens interleukin 15 receptor subunit alpha (IL15RA), transcript variant 3, mRNA.
Gene ID
3601
UniProt
Q13261
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Field of Research
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IL15RA
Overview
Carrier-free (BSA/glycerol-free) IL15RA mouse monoclonal antibody, clone LBI6B2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3601
Uniprot URL
https://www.uniprot.org/uniprot/Q13261
Curated Selection
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