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ACSL5 Mouse Monoclonal Antibody [Clone ID: LBI1C6]

Product Specifications

Background

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

ACS2; ACS5; FACL5

Gene Name

Homo sapiens acyl-CoA synthetase long chain family member 5 (ACSL5), transcript variant 2, mRNA.

Gene ID

51703

UniProt

Q9ULC5

Conjugation

Unconjugated

Related Pathways

Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway

Field of Research

Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway

Dilution

WB 1:500~2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ACSL5

Overview

Carrier-free (BSA/glycerol-free) ACSL5 mouse monoclonal antibody, clone LBI1C6

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=51703

Uniprot URL

https://www.uniprot.org/uniprot/Q9ULC5

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