RFC3 Mouse Monoclonal Antibody [Clone ID: LBI3F6]
Product Specifications
Background
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
RFC38
Gene Name
Homo sapiens replication factor C subunit 3 (RFC3), transcript variant 1, mRNA.
Gene ID
5983
UniProt
P40938
Conjugation
Unconjugated
Related Pathways
DNA replication, Mismatch repair, Nucleotide excision repair
Field of Research
DNA replication, Mismatch repair, Nucleotide excision repair
Dilution
WB 1:500, IHC 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RFC3
Overview
Carrier-free (BSA/glycerol-free) RFC3 mouse monoclonal antibody, clone LBI3F6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5983
Uniprot URL
https://www.uniprot.org/uniprot/P40938
Curated Selection
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