RFC3 Mouse Monoclonal Antibody [Clone ID: LBI3F6]

Product Specifications

Background

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) RFC3 mouse monoclonal antibody, clone LBI3F6

Synonyms

RFC38

Gene Name

Homo sapiens replication factor C subunit 3 (RFC3), transcript variant 1, mRNA.

Gene ID

5983

UniProt

P40938

Conjugation

Unconjugated

Related Pathways

DNA replication, Mismatch repair, Nucleotide excision repair

Field of Research

DNA replication, Mismatch repair, Nucleotide excision repair

Dilution

WB 1:500, IHC 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.