FHIT Mouse Monoclonal Antibody [Clone ID: LBI6B4]
Product Specifications
Background
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Overview
Carrier-free (BSA/glycerol-free) FHIT mouse monoclonal antibody, clone LBI6B4
Synonyms
AP3Aase; FRA3B
Gene Name
Homo sapiens fragile histidine triad diadenosine triphosphatase (FHIT), transcript variant 1, mRNA.
Gene ID
2272
UniProt
P49789
Conjugation
Unconjugated
Related Pathways
Non-small cell lung cancer, Purine metabolism, Small cell lung cancer
Field of Research
Non-small cell lung cancer, Purine metabolism, Small cell lung cancer
Dilution
WB 1:2000, IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FHIT
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2272
Uniprot URL
https://www.uniprot.org/uniprot/P49789
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