NIRF (UHRF2) Mouse Monoclonal Antibody [Clone ID: LBI4E10]

Product Specifications

Background

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

Overview

Carrier-free (BSA/glycerol-free) UHRF2 mouse monoclonal antibody, clone LBI4E10

Synonyms

NIRF; RNF107; TDRD23; URF2

Gene Name

Homo sapiens ubiquitin like with PHD and ring finger domains 2 (UHRF2), transcript variant 1, mRNA.

Gene ID

115426

UniProt

Q96PU4

Conjugation

Unconjugated

Dilution

WB 1:500~2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.