RHOH Mouse Monoclonal Antibody [Clone ID: LBI9F4]

Product Specifications

Background

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP) -metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]

Overview

Carrier-free (BSA/glycerol-free) RHOH mouse monoclonal antibody, clone LBI9F4

Synonyms

ARHH; TTF

Gene Name

Homo sapiens ras homolog family member H (RHOH), transcript variant 6, mRNA.

Gene ID

399

UniProt

Q15669

Conjugation

Unconjugated

Related Pathways

Leukocyte transendothelial migration

Field of Research

Leukocyte transendothelial migration

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.