IQGAP1 Mouse Monoclonal Antibody [Clone ID: LBI7F5]
Product Specifications
Background
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
Synonyms
HUMORFA01; p195; SAR1
Gene Name
Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA.
Gene ID
8826
UniProt
P46940
Conjugation
Unconjugated
Related Pathways
Adherens junction, Regulation of actin cytoskeleton
Field of Research
Adherens junction, Regulation of actin cytoskeleton
Dilution
WB 1:500~2000, IHC 1:5000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IQGAP1
Overview
Carrier-free (BSA/glycerol-free) IQGAP1 mouse monoclonal antibody, clone LBI7F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8826
Uniprot URL
https://www.uniprot.org/uniprot/P46940
Curated Selection
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