PRMT7 Mouse Monoclonal Antibody [Clone ID: LBI9B7]

Product Specifications

Background

Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing (Miranda et al., 2004 [PubMed 15044439]) . [supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) lacks an exon in the 5' UTR and in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK304605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025087, ERS025093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

Overview

Carrier-free (BSA/glycerol-free) PRMT7 mouse monoclonal antibody, clone LBI9B7

Synonyms

FLJ10640; KIAA1933

Gene Name

Homo sapiens protein arginine methyltransferase 7 (PRMT7), transcript variant 1, mRNA.

Gene ID

54496

UniProt

Q9NVM4

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.