TIMM8A Mouse Monoclonal Antibody [Clone ID: LBI5C8]
Product Specifications
Background
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2009]
Synonyms
DDP; DDP1; DFN1; MTS; TIM8
Gene Name
Homo sapiens translocase of inner mitochondrial membrane 8A (TIMM8A), transcript variant 1, mRNA; nuclear gene for mitochondrial product.
Gene ID
1678
UniProt
O60220
Conjugation
Unconjugated
Dilution
WB 1:500~2000, IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TIMM8A
Overview
Carrier-free (BSA/glycerol-free) TIMM8A mouse monoclonal antibody, clone LBI5C8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1678
Uniprot URL
https://www.uniprot.org/uniprot/O60220
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
