WDR77 Mouse Monoclonal Antibody [Clone ID: LBI1F7]

Product Specifications

Background

WDR77 is a component of the 20S PRMT5 (MIM 604045) -containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061) . This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]) . [supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016946.1, BC001679.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##

Overview

Carrier-free (BSA/glycerol-free) WDR77 mouse monoclonal antibody, clone LBI1F7

Synonyms

HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50

Gene Name

Homo sapiens WD repeat domain 77 (WDR77), transcript variant 2, mRNA.

Gene ID

79084

UniProt

Q9BQA1

Conjugation

Unconjugated

Dilution

WB 1:500~2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.