Myotilin (MYOT) Mouse Monoclonal Antibody [Clone ID: LBI5E11]

Product Specifications

Background

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]

Overview

Carrier-free (BSA/glycerol-free) MYOT mouse monoclonal antibody, clone LBI5E11

Synonyms

LGMD1; LGMD1A; MFM3; TTID; TTOD

Gene Name

Homo sapiens myotilin (MYOT), transcript variant 1, mRNA.

Gene ID

9499

UniProt

Q9UBF9

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:1000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.