RBPJK (RBPJ) Mouse Monoclonal Antibody [Clone ID: LBI4B11]
Product Specifications
Background
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Synonyms
AOS3; CBF1; csl; IGKJRB; IGKJRB1; KBF2; RBP-J; RBPJK; RBPSUH; SUH
Gene Name
Homo sapiens recombination signal binding protein for immunoglobulin kappa J region (RBPJ), transcript variant 1, mRNA.
Gene ID
3516
UniProt
Q06330
Conjugation
Unconjugated
Related Pathways
Notch signaling pathway
Field of Research
Notch signaling pathway
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RBPJ
Overview
Carrier-free (BSA/glycerol-free) RBPJ mouse monoclonal antibody, clone LBI4B11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3516
Uniprot URL
https://www.uniprot.org/uniprot/Q06330
Curated Selection
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