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N-Myc (MYCN) Mouse Monoclonal Antibody [Clone ID: LBI2E5]

Product Specifications

Background

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Synonyms

BHLHe37; MODED; N-myc; NMYC; ODED

Gene Name

Homo sapiens MYCN proto-oncogene, bHLH transcription factor (MYCN), transcript variant 2, mRNA.

Gene ID

4613

UniProt

P04198

Conjugation

Unconjugated

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

MYCN

Overview

Carrier-free (BSA/glycerol-free) MYCN mouse monoclonal antibody, clone LBI2E5

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4613

Uniprot URL

https://www.uniprot.org/uniprot/P04198

Curated Selection

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