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TGF beta Receptor III (TGFBR3) Mouse Monoclonal Antibody [Clone ID: LBI4F11]

Product Specifications

Background

This locus encodes the transforming growth factor (TGF) -beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2010]

Synonyms

Betaglycan; BGCAN

Gene Name

Homo sapiens transforming growth factor beta receptor 3 (TGFBR3), transcript variant 1, mRNA.

Gene ID

7049

UniProt

Q03167

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

TGFBR3

Overview

Carrier-free (BSA/glycerol-free) TGFBR3 mouse monoclonal antibody, clone LBI4F11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7049

Uniprot URL

https://www.uniprot.org/uniprot/Q03167

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