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BNP (NPPB) Mouse Monoclonal Antibody [Clone ID: LBI2C9]

Product Specifications

Background

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) NPPB mouse monoclonal antibody, clone LBI2C9

Synonyms

BNP; Iso-ANP

Gene Name

Homo sapiens natriuretic peptide B (NPPB), mRNA.

Gene ID

4879

UniProt

P16860

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

NPPB

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4879

Uniprot URL

https://www.uniprot.org/uniprot/P16860

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