SPI1 Mouse Monoclonal Antibody [Clone ID: LBI1F3]
Product Specifications
Background
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
OF; PU.1; SFPI1; SPI-1; SPI-A
Gene Name
Homo sapiens Spi-1 proto-oncogene (SPI1), transcript variant 2, mRNA.
Gene ID
6688
UniProt
P17947
Conjugation
Unconjugated
Related Pathways
Acute myeloid leukemia, Pathways in cancer
Field of Research
Acute myeloid leukemia, Pathways in cancer
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SPI1
Overview
Carrier-free (BSA/glycerol-free) SPI1 mouse monoclonal antibody, clone LBI1F3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6688
Uniprot URL
https://www.uniprot.org/uniprot/P17947
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