SPI1 Mouse Monoclonal Antibody [Clone ID: LBI1F3]

Product Specifications

Background

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) SPI1 mouse monoclonal antibody, clone LBI1F3

Synonyms

OF; PU.1; SFPI1; SPI-1; SPI-A

Gene Name

Homo sapiens Spi-1 proto-oncogene (SPI1), transcript variant 2, mRNA.

Gene ID

6688

UniProt

P17947

Conjugation

Unconjugated

Related Pathways

Acute myeloid leukemia, Pathways in cancer

Field of Research

Acute myeloid leukemia, Pathways in cancer

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.