SHMT2 Mouse Monoclonal Antibody [Clone ID: LBI1E6]

Product Specifications

Background

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Overview

Carrier-free (BSA/glycerol-free) SHMT2 mouse monoclonal antibody, clone LBI1E6

Synonyms

GLYA; HEL-S-51e; NEDCASB; SHMT

Gene Name

Homo sapiens serine hydroxymethyltransferase 2 (SHMT2), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

Gene ID

6472

UniProt

P34897

Conjugation

Unconjugated

Related Pathways

Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Methane metabolism, One carbon pool by folate

Field of Research

Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Methane metabolism, One carbon pool by folate

Dilution

IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.