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Amelotin (AMTN) Mouse Monoclonal Antibody [Clone ID: LBI1D6]

Product Specifications

Background

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]) . [supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC121812.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

Overview

Carrier-free (BSA/glycerol-free) AMTN mouse monoclonal antibody, clone LBI1D6

Synonyms

UNQ689

Gene Name

Homo sapiens amelotin (AMTN), transcript variant 1, mRNA.

Gene ID

401138

UniProt

Q6UX39

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

AMTN

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=401138

Uniprot URL

https://www.uniprot.org/uniprot/Q6UX39

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