CDC6 Mouse Monoclonal Antibody [Clone ID: LBI1B3]

Product Specifications

Background

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) CDC6 mouse monoclonal antibody, clone LBI1B3

Synonyms

CDC18L; HsCDC6; HsCDC18

Gene Name

Homo sapiens cell division cycle 6 (CDC6), mRNA.

Gene ID

990

UniProt

Q99741

Conjugation

Unconjugated

Related Pathways

Cell cycle

Field of Research

Cell cycle

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.