HDAC2 Mouse Monoclonal Antibody [Clone ID: LBI7E10]
Product Specifications
Background
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4) . This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Overview
Carrier-free (BSA/glycerol-free) HDAC2 mouse monoclonal antibody, clone LBI7E10
Synonyms
HD2; RPD3; YAF1
Gene Name
Homo sapiens histone deacetylase 2 (HDAC2), transcript variant 1, mRNA.
Gene ID
3066
UniProt
Q92769
Conjugation
Unconjugated
Related Pathways
Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer
Field of Research
Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HDAC2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3066
Uniprot URL
https://www.uniprot.org/uniprot/Q92769
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