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ASB2 Mouse Monoclonal Antibody [Clone ID: LBI2A2]

Product Specifications

Background

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Synonyms

ASB-2

Gene Name

Homo sapiens ankyrin repeat and SOCS box containing 2 (ASB2), transcript variant 2, mRNA.

Gene ID

51676

UniProt

Q96Q27

Conjugation

Unconjugated

Dilution

IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ASB2

Overview

Carrier-free (BSA/glycerol-free) ASB2 mouse monoclonal antibody, clone LBI2A2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=51676

Uniprot URL

https://www.uniprot.org/uniprot/Q96Q27

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