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FOLR2 Mouse Monoclonal Antibody [Clone ID: LBI8G1]

Product Specifications

Background

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) FOLR2 mouse monoclonal antibody, clone LBI8G1

Synonyms

BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3

Gene Name

Homo sapiens folate receptor beta (FOLR2), transcript variant 1, mRNA.

Gene ID

2350

UniProt

P14207

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

FOLR2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2350

Uniprot URL

https://www.uniprot.org/uniprot/P14207

Frequently Asked Questions

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