URP2 (FERMT3) Mouse Monoclonal Antibody [Clone ID: LBI3C7]

Product Specifications

Background

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III) . Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]

Overview

Carrier-free (BSA/glycerol-free) FERMT3 mouse monoclonal antibody, clone LBI3C7

Synonyms

KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF

Gene Name

Homo sapiens FERM domain containing kindlin 3 (FERMT3), transcript variant URP2SF, mRNA.

Gene ID

83706

UniProt

Q86UX7

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.