Jagged1 (JAG1) Mouse Monoclonal Antibody [Clone ID: LBI3A10]

Product Specifications

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) JAG1 mouse monoclonal antibody, clone LBI3A10

Synonyms

AGS; AGS1; AHD; AWS; CD339; HJ1; JAGL1

Gene Name

Homo sapiens jagged canonical Notch ligand 1 (JAG1), mRNA.

Gene ID

182

UniProt

P78504

Conjugation

Unconjugated

Related Pathways

Notch signaling pathway

Field of Research

Notch signaling pathway

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.