CD22 Mouse Monoclonal Antibody [Clone ID: LBI8E6]

Product Specifications

Background

Predominantly monomer of isoform CD22-beta. Also found as heterodimer of isoform CD22-beta and a shorter isoform. Interacts with PTPN6/SHP-1, LYN, SYK, PIK3R1/PIK3R2 and PLCG1 upon phosphorylation. Interacts with GRB2, INPP5D and SHC1 upon phosphorylation (By similarity) . May form a complex with INPP5D/SHIP, GRB2 and SHC1. [UniProtKB/Swiss-Prot Function]

Overview

Carrier-free (BSA/glycerol-free) CD22 mouse monoclonal antibody, clone LBI8E6

Synonyms

SIGLEC-2; SIGLEC2

Gene Name

Homo sapiens CD22 molecule (CD22), transcript variant 1, mRNA.

Gene ID

933

UniProt

P20273

Conjugation

Unconjugated

Related Pathways

B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Field of Research

B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.