CD22 Mouse Monoclonal Antibody [Clone ID: LBI8E6]
Product Specifications
Background
Predominantly monomer of isoform CD22-beta. Also found as heterodimer of isoform CD22-beta and a shorter isoform. Interacts with PTPN6/SHP-1, LYN, SYK, PIK3R1/PIK3R2 and PLCG1 upon phosphorylation. Interacts with GRB2, INPP5D and SHC1 upon phosphorylation (By similarity) . May form a complex with INPP5D/SHIP, GRB2 and SHC1. [UniProtKB/Swiss-Prot Function]
Synonyms
SIGLEC-2; SIGLEC2
Gene Name
Homo sapiens CD22 molecule (CD22), transcript variant 1, mRNA.
Gene ID
933
UniProt
P20273
Conjugation
Unconjugated
Related Pathways
B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage
Field of Research
B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD22
Overview
Carrier-free (BSA/glycerol-free) CD22 mouse monoclonal antibody, clone LBI8E6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=933
Uniprot URL
https://www.uniprot.org/uniprot/P20273
Curated Selection
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