APPL (APPL1) Mouse Monoclonal Antibody [Clone ID: LBI4B11]
Product Specifications
Background
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Synonyms
APPL; DIP13alpha; MODY14
Gene Name
Homo sapiens adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), mRNA.
Gene ID
26060
UniProt
Q9UKG1
Conjugation
Unconjugated
Related Pathways
Colorectal cancer, Pathways in cancer
Field of Research
Colorectal cancer, Pathways in cancer
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
APPL1
Overview
Carrier-free (BSA/glycerol-free) APPL1 mouse monoclonal antibody, clone LBI4B11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=26060
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKG1
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