APPL (APPL1) Mouse Monoclonal Antibody [Clone ID: LBI7C3]

Product Specifications

Background

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) APPL1 mouse monoclonal antibody, clone LBI7C3

Synonyms

APPL; DIP13alpha; MODY14

Gene Name

Homo sapiens adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), mRNA.

Gene ID

26060

UniProt

Q9UKG1

Conjugation

Unconjugated

Related Pathways

Colorectal cancer, Pathways in cancer

Field of Research

Colorectal cancer, Pathways in cancer

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.