GPNMB Mouse Monoclonal Antibody [Clone ID: LBI2A10]

Product Specifications

Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) GPNMB mouse monoclonal antibody, clone LBI2A10

Synonyms

HGFIN; NMB

Gene Name

Homo sapiens glycoprotein nmb (GPNMB), transcript variant 1, mRNA.

Gene ID

10457

UniProt

Q14956

Conjugation

Unconjugated

Dilution

WB 1:500, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.