GPNMB Mouse Monoclonal Antibody [Clone ID: LBI2A10]
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
HGFIN; NMB
Gene Name
Homo sapiens glycoprotein nmb (GPNMB), transcript variant 1, mRNA.
Gene ID
10457
UniProt
Q14956
Conjugation
Unconjugated
Dilution
WB 1:500, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GPNMB
Overview
Carrier-free (BSA/glycerol-free) GPNMB mouse monoclonal antibody, clone LBI2A10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10457
Uniprot URL
https://www.uniprot.org/uniprot/Q14956
Curated Selection
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