DR4 (TNFRSF10A) Mouse Monoclonal Antibody [Clone ID: LBI11B12]
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms
APO2; CD261; DR4; TRAILR-1; TRAILR1
Gene Name
Homo sapiens TNF receptor superfamily member 10a (TNFRSF10A), mRNA.
Gene ID
8797
UniProt
O00220
Conjugation
Unconjugated
Related Pathways
Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
Field of Research
Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF10A
Overview
Carrier-free (BSA/glycerol-free) TNFRSF10A mouse monoclonal antibody, clone LBI11B12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8797
Uniprot URL
https://www.uniprot.org/uniprot/O00220
Curated Selection
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