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CYP7B1 Mouse Monoclonal Antibody [Clone ID: LBI1G7]

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) CYP7B1 mouse monoclonal antibody, clone LBI1G7

Synonyms

CBAS3; CP7B; SPG5A

Gene Name

Homo sapiens cytochrome P450 family 7 subfamily B member 1 (CYP7B1), transcript variant 1, mRNA.

Gene ID

9420

UniProt

O75881

Conjugation

Unconjugated

Related Pathways

Primary bile acid biosynthesis

Field of Research

Primary bile acid biosynthesis

Dilution

WB 1:500, IHC 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, P450, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CYP7B1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9420

Uniprot URL

https://www.uniprot.org/uniprot/O75881

Frequently Asked Questions

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