CYP7B1 Mouse Monoclonal Antibody [Clone ID: LBI1G7]
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) CYP7B1 mouse monoclonal antibody, clone LBI1G7
Synonyms
CBAS3; CP7B; SPG5A
Gene Name
Homo sapiens cytochrome P450 family 7 subfamily B member 1 (CYP7B1), transcript variant 1, mRNA.
Gene ID
9420
UniProt
O75881
Conjugation
Unconjugated
Related Pathways
Primary bile acid biosynthesis
Field of Research
Primary bile acid biosynthesis
Dilution
WB 1:500, IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, P450, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CYP7B1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9420
Uniprot URL
https://www.uniprot.org/uniprot/O75881
Frequently Asked Questions
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