PDX1 Mouse Monoclonal Antibody [Clone ID: LBI7F7]
Product Specifications
Background
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4) . [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) PDX1 mouse monoclonal antibody, clone LBI7F7
Synonyms
GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Gene Name
Homo sapiens pancreatic and duodenal homeobox 1 (PDX1), mRNA.
Gene ID
3651
UniProt
P52945
Conjugation
Unconjugated
Related Pathways
Maturity onset diabetes of the young, Type II diabetes mellitus
Field of Research
Maturity onset diabetes of the young, Type II diabetes mellitus
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDX1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3651
Uniprot URL
https://www.uniprot.org/uniprot/P52945
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