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PON3 Mouse Monoclonal Antibody [Clone ID: LBI4H9]

Product Specifications

Background

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL) . The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]

Synonyms

Lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase

Gene Name

Homo sapiens paraoxonase 3 (PON3), mRNA.

Gene ID

5446

UniProt

Q15166

Conjugation

Unconjugated

Related Pathways

Metabolic pathways

Field of Research

Metabolic pathways

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PON3

Overview

Carrier-free (BSA/glycerol-free) PON3 mouse monoclonal antibody, clone LBI4H9

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5446

Uniprot URL

https://www.uniprot.org/uniprot/Q15166

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