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PAPSS2 Mouse Monoclonal Antibody [Clone ID: LBI7E8]

Product Specifications

Background

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Synonyms

ATPSK2; BCYM4; SK2

Gene Name

Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2), transcript variant 1, mRNA.

Gene ID

9060

UniProt

O95340

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism

Field of Research

Metabolic pathways, Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism

Dilution

IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PAPSS2

Overview

Carrier-free (BSA/glycerol-free) PAPSS2 mouse monoclonal antibody, clone LBI7E8

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9060

Uniprot URL

https://www.uniprot.org/uniprot/O95340

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