PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: LBI27E8]

Product Specifications

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody, clone LBI27E8

Synonyms

CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2

Gene Name

Homo sapiens programmed cell death 1 (PDCD1), mRNA.

Gene ID

5133

UniProt

Q15116

Conjugation

Unconjugated

Related Pathways

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Field of Research

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Dilution

FLOW 1:50

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.