Ezrin (EZR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]
Product Specifications
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CVIL; CVL; HEL-S-105; VIL2
Gene Name
Homo sapiens ezrin (EZR), transcript variant 1, mRNA.
Gene ID
7430
UniProt
P15311
Conjugation
Unconjugated
Related Pathways
Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
Field of Research
Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
Dilution
WB 1:500, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
EZR
Overview
Carrier-free (BSA/glycerol-free) EZR mouse monoclonal antibody, clone LBI1F3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7430
Uniprot URL
https://www.uniprot.org/uniprot/P15311
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