Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: LBI2F5]

Product Specifications

Background

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Overview

Carrier-free (BSA/glycerol-free) KRT8 mouse monoclonal antibody, clone LBI2F5

Synonyms

CARD2; CK-8; CK8; CYK8; K2C8; K8; KO

Gene Name

Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.

Gene ID

3856

UniProt

P05787

Conjugation

Unconjugated

Dilution

IHC 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.