PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: LBI14B3]
Product Specifications
Background
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Synonyms
CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Gene Name
Homo sapiens programmed cell death 1 (PDCD1), mRNA.
Gene ID
5133
UniProt
Q15116
Conjugation
Unconjugated
Related Pathways
Cell adhesion molecules (CAMs), T cell receptor signaling pathway
Field of Research
Cell adhesion molecules (CAMs), T cell receptor signaling pathway
Dilution
WB 1:2000, IF 1:100~900, FLOW 1:50
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDCD1
Overview
Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody, clone LBI14B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5133
Uniprot URL
https://www.uniprot.org/uniprot/Q15116
Curated Selection
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