Dishevelled 2 (DVL2) Mouse Monoclonal Antibody [Clone ID: LBI2E11]

Product Specifications

Background

This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (glycerol/BSA-free) DVL2 mouse monoclonal antibody, clone LBI2E11

Synonyms

Dishevelled; dishevelled 2; dishevelled 2 (homologous to Drosophila dsh) ; DSH homolog 2; dsh homolog 2 (Drosophila) ; segment polarity protein dishevelled homolog DVL-2

Gene Name

Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.

Gene ID

1856

UniProt

O14641

Conjugation

Unconjugated

Related Pathways

Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

Field of Research

Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, ES Cell Differentiation/IPS

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.