VEGF Receptor 1 (FLT1) Mouse Monoclonal Antibody [Clone ID: LBI11G5]

Product Specifications

Background

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. [provided by RefSeq, May 2009]

Overview

Carrier-free (BSA/glycerol-free) FLT1 mouse monoclonal antibody, clone LBI11G5

Synonyms

FLT; FLT-1; VEGFR-1; VEGFR1

Gene Name

Homo sapiens fms related receptor tyrosine kinase 1 (FLT1), transcript variant 1, mRNA.

Gene ID

2321

UniProt

P17948

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

Field of Research

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protein Kinase, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.