Osteopontin (SPP1) Mouse Monoclonal Antibody [Clone ID: LBI5E4]
Product Specifications
Background
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms
BNSP; BSPI; ETA-1; OPN
Gene Name
Homo sapiens secreted phosphoprotein 1 (SPP1), transcript variant 1, mRNA.
Gene ID
6696
UniProt
P10451
Conjugation
Unconjugated
Related Pathways
ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway
Field of Research
ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SPP1
Overview
Carrier-free (BSA/glycerol-free) SPP1 mouse monoclonal antibody, clone LBI5E4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6696
Uniprot URL
https://www.uniprot.org/uniprot/P10451
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