PHGDH Mouse Monoclonal Antibody [Clone ID: LBI4A1]

Product Specifications

Background

This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

Overview

Carrier-free (BSA/glycerol-free) PHGDH mouse monoclonal antibody, clone LBI4A1

Synonyms

3-PGDH; 3PGDH; HEL-S-113; NLS; NLS1; PDG; PGAD; PGD; PGDH; PHGDHD; SERA

Gene Name

Homo sapiens phosphoglycerate dehydrogenase (PHGDH), mRNA.

Gene ID

26227

UniProt

O43175

Conjugation

Unconjugated

Related Pathways

Glycine, serine and threonine metabolism, Metabolic pathways

Field of Research

Glycine, serine and threonine metabolism, Metabolic pathways

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.