DUSP10 Mouse Monoclonal Antibody [Clone ID: LBI1F2]

Product Specifications

Background

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Overview

Carrier-free (BSA/glycerol-free) DUSP10 mouse monoclonal antibody, clone LBI1F2

Synonyms

MKP-5; MKP5

Gene Name

Homo sapiens dual specificity phosphatase 10 (DUSP10), transcript variant 1, mRNA.

Gene ID

11221

UniProt

Q9Y6W6

Conjugation

Unconjugated

Related Pathways

MAPK signaling pathway

Field of Research

MAPK signaling pathway

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Phosphatase

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.