GABA A Receptor alpha 5 (GABRA5) Mouse Monoclonal Antibody [Clone ID: LBI3H7]
Product Specifications
Background
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) GABRA5 mouse monoclonal antibody, clone LBI3H7
Synonyms
MGC138184
Gene Name
Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha5 (GABRA5), transcript variant 1, mRNA.
Gene ID
2558
UniProt
P31644
Conjugation
Unconjugated
Related Pathways
Neuroactive ligand-receptor interaction
Field of Research
Neuroactive ligand-receptor interaction
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GABRA5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2558
Uniprot URL
https://www.uniprot.org/uniprot/P31644
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