Z-VDVA- (DL-Asp) -FMK
Z-VDVA- (DL-Asp) -FMK is a Z-VDVAD-FMK derivative. Z-VDVAD-FMK (HY-P1008) is a special inhibitor of caspase-2[1].
Product Specifications
CAS Number
[1926163-61-2]
Product Name Alternative
Z-VD (OMe) VAD (OMe) - (DL-Asp) -FMK
UNSPSC
12352005
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/z-vdva-dl-asp-fmk.html
Solubility
10 mM in DMSO
Smiles
COC(CC(C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O)=O)=O
Molecular Formula
C32H46FN5O11
Molecular Weight
695.73
References & Citations
[1]Gamen S, et al. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells. Exp Cell Res. 2000;258 (1) :223-235.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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