Neurofilament (NEFM) Mouse Monoclonal Antibody [Clone ID: LBI5B7]
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Synonyms
NEF3; NF-M; NFM
Gene Name
Homo sapiens neurofilament medium chain (NEFM), transcript variant 1, mRNA.
Gene ID
4741
UniProt
P07197
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS)
Field of Research
Amyotrophic lateral sclerosis (ALS)
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEFM
Overview
Carrier-free (BSA/glycerol-free) NEFM mouse monoclonal antibody, clone LBI5B7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4741
Uniprot URL
https://www.uniprot.org/uniprot/P07197
Curated Selection
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