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Progesterone Receptor (PGR) Mouse Monoclonal Antibody [Clone ID: LBI4A11]

Product Specifications

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011]

Synonyms

NR3C3; PR

Gene Name

Homo sapiens progesterone receptor (PGR), transcript variant 2, mRNA.

Gene ID

5241

UniProt

P06401

Conjugation

Unconjugated

Related Pathways

Oocyte meiosis, Progesterone-mediated oocyte maturation

Field of Research

Oocyte meiosis, Progesterone-mediated oocyte maturation

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PGR

Overview

Carrier-free (BSA/glycerol-free) PGR mouse monoclonal antibody, clone LBI4A11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5241

Uniprot URL

https://www.uniprot.org/uniprot/P06401

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