COX2 (PTGS2) Mouse Monoclonal Antibody [Clone ID: LBI2F10]
Product Specifications
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Overview
Carrier-free (BSA/glycerol-free) PTGS2 mouse monoclonal antibody, clone LBI2F10
Synonyms
COX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2
Gene Name
Homo sapiens prostaglandin-endoperoxide synthase 2 (PTGS2), mRNA.
Gene ID
5743
UniProt
P35354
Conjugation
Unconjugated
Related Pathways
Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway
Field of Research
Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PTGS2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5743
Uniprot URL
https://www.uniprot.org/uniprot/P35354
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