COX2 (PTGS2) Mouse Monoclonal Antibody [Clone ID: LBI2F10]

Product Specifications

Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Overview

Carrier-free (BSA/glycerol-free) PTGS2 mouse monoclonal antibody, clone LBI2F10

Synonyms

COX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2

Gene Name

Homo sapiens prostaglandin-endoperoxide synthase 2 (PTGS2), mRNA.

Gene ID

5743

UniProt

P35354

Conjugation

Unconjugated

Related Pathways

Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway

Field of Research

Arachidonic acid metabolism, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.